Test Code LAB26 Gentamicin Trough

Specimen Requirements

Container/Tube:
Preferred: Lithium Heparin (Green Top)
Acceptable: Serum (Red Top)
Specimen Volume: 1mL

Stability:

Temperature	Time
Room Temp 18-28°C	2 hours
Refrigerated 2–8°C	7 days
Frozen <-18°C	14 days

Additional Instructions

Spin and remove from cells within 1 hour.
Designate last dose date and time.

Therapeutic Range

Gentamicin level, trough: 0.5-2 mcg/ml

Toxic: Trough >2 mcg/ml

Additional Information

Collection Time After Administration:
Traditional-intermittent regimen: should be drawn at steady state, after 2nd or 3rd maintenance dose
Peak: Collect 30 minutes after IV infusion or 1 hour after IM injection
Trough: 30-60 min prior to next dose

Extended-interval regimen (high-dose):
Random level: Collect 6-14 hours post dose, (pharmacist to use nomogram for dosing)
Trough: 30-60 min prior to second dose

Synonyms

Chemistry

Department